Pain Relief & Treatment

The Microsurgery Spine & Pain Institute in Plano, Texas offers Prolotherapy as one of the many treatment options for joint pain relief. Call us today for more information or to schedule an appointment.



Proliferative therapy, or prolotherapy, treats the body by boosting its healing process for injured joints or tissue. Physicians carry out prolotherapy by injecting a specific mixture into the body at the site of an injury to speed the healing process. Prolotherapy involves using one’s own cells from bone marrow, blood or fat and injecting them into an area of pain or injury. Several forms of prolotherapy exist and are used to repair injured tissues.

Prolotherapy takes fibroblasts, or cells used for wound healing that are found in connective tissues, and chondrocytes, or cells that exist in cartilage, and proliferates them. By using stem cells produced by the body, which are called adult or mesenchymal stem cells, the physician injects the MSCs at the area of injury and the cells repair the structure and restore the function of the injured body part, like an injured disc. Physicians take MSCs from bone marrow or fat using a local anesthetic and a needle at the hip. The physician then transfers the harvested stem cells to the site of injury by injection. The prolotherapy procedure lasts about 10 minutes and results in mild soreness. Prolotherapy treatments can be used for a number of conditions including lower back pain, joint pain, hip pain and knee pain.

Dextrose prolotherapy was the original prolotherapy procedure and began in the early 20th century. Physicians used sugar, saltwater or other substances to inject at the site of an injury. The formula caused irritation at the spot of pain, sending growth factors racing to the site of injection to begin the healing process. Platelet-rich plasma therapy stimulates growth factors for injuries as well. With PRP, physicians performing the procedure draw a patient’s blood and separate the invasive surgery alternative from the rest of the blood by spinning the substance in a centrifuge. The spinning motion causes the platelets to become very concentrated and strengthen in healing power. A physician then injects the invasive surgery alternative into the patient’s body. The invasive surgery alternative contains proteins that spur healing with amplified power as opposed to the normalcy of unmodified growth factor healing.




Prolotherapy benefits patients by increasing joint mobility, reducing pain and stimulating growth of new cells to rebuild injured joints or tissue. Prolotherapy relieves pain all over the body, including spinal pain. There are very few risks involved in prolotherapy. Prolotherapy bears a much lower risk than surgery, which involves invasion and anesthesia. Surgery can also cause additional lifelong problems. One of the most important elements of the therapy process is the physician’s experience and the quality of care. Dr. Gabriel Rodriguez and the staff at The Pain Relief Center are well trained in prolotherapy, as well as PRP, and are ready to serve the communities of Dallas, Plano, Frisco, McKinney, Allen and Carrollton.

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